Haemolytics tests

Arrow In this section

Here is a list of the haemolytics tests carried out by the Haematology department, together with specimen requirements and the estimated time it will take to produce a result.

The results availability times given here represent the time generally required to produce a result following receipt of the sample in the laboratory. Sample transport times are not included.

Where appropriate, if a result is required the same day samples must be received sufficiently early to allow completion of the test. Contact the lab if the test you require is not listed.

Inform the laboratory if a test is to be performed urgently.

These tests are available during the normal working day. See a list of haematology tests available outside core working hours.

For further advice or information call 0161 276 4689.

All requests for genetic diagnosis in haemoglobinopathy which are approved under the NW SHA Indications for Genetic Diagnosis of Haemoglobinopathy algorithm are centrally funded. Find associated forms and guidance from the Manchester Haemoglobinopathy Diagnostic Service.

For haemoglobinopathy genetic studies, contact Dr Steve Keeney, Molecular Diagnostics Centre, 0161 276 4809.

For Red Cell Haemolytic Screen contact the laboratory on 0161 276 4689.

Test

 

(performed at ORC/Trafford)

Specimen requirements

Urgent results available (from time of receipt in lab)

Inform the lab if a test is to be performed immediately

Non-urgent results available (from time of receipt in lab) Report available

Urgent/pre-operative HbS screening test (Pts > 1 yr old)

 

(ORC/T)

1x 3.4ml red cap EDTA

[1x 1.2ml red cap EDTA – inform the laboratory if a test is to be perfomed urgently]

30min 24hr 10-14 workdays

Routine Haemoglobinopathy Screening

(T)

1x 3.4ml red cap EDTA

[1x 1.2ml red cap EDTA – inform the laboratory if a test is to be perfomed urgently]

N/A 10 workdays

10-14 workdays

 

Universal Antenatal Haemoglobinopathy Screening

 

(T)

1x 3.4ml red cap EDTA

[1x 1.2ml red cap EDTA – inform the laboratory if a test is to be perfomed urgently]

Provisional report: 3 workdays 5 workdays 7 workdays

DNA Testing for the Haemoglobinopathies

(North West Genetic Diagnostic Service for Haemoglobinopathy

Support with advice on Haemoglobinopathy results please see: Information on Haemoglobinopathy Carrier States for health professionals)

(ORC)

4 x 3.4ml EDTA N/A N/A N/A

G6PD Screen

 

(ORC)

1x 3.4ml red cap EDTA

[1x 1.2ml red cap EDTA – inform the laboratory if a test is to be perfomed urgently]

Within 4 hours

Inform the laboratory if a test is to be performed urgently.

Telephone the laboratory – samples screened on Fridays by arrangement with laboratory.

3 workdays 5 workdays

G6PD Assay (if screen gives intermediate or reduced result)

 

(ORC)

1x 3.4ml red cap EDTA

[1x 1.2ml red cap EDTA – inform the laboratory if a test is to be perfomed urgently]

N/A 3 workdays 5 workdays

Reference ranges – Haemolytics

These reference ranges are to help with interpreting results of Haemolytics tests carried out by the Haematology department.

 

Haemoglobin A2 2.3 – 3.3%
Haemoglobin F < 1.5%
G6PD

4.8 – 13.6 ug/l

8.3 – 20.1 ug/l 0-9 months

Factors affecting the results or processing of haematinics and haemolytics tests

Here are some of the factors which could affect the results or processing of haematinics and haemolytics tests. This is not an exhaustive list. There may be other factors affecting the reporting of results which are not listed.

 

Test Factors affecting result/processing Outcome
Ferritin, B12, Serum folate

Only EDTA sent

Would not process
Haematinic assays Haemolysis Would process and add appropriate comment
Haemolytic assays EDTA clotted Would not process
Plasma Viscosity Sample stored in fridge Would not process

(Last reviewed October 2018)