Dr Mars SkaeConsultant Paediatric Endocrinologist, Lead clinician for Paediatric Obesity and Disorders of Sex Development
MB ChB (Sheffield), MRCPH, MPhil
Congenital Hyperinsulinism, Obesity, Disorders of Sex Development (DSD), Transition and adolescent endocrinology, Metabolic bone medicine including skeletal dysplasias.
A Malaysian by birth, Mars moved to the United Kingdom to read medicine at Sheffield University and graduated in 1998, followed by obtaining membership to the Royal College of Paediatrics and Child Health and completing her training in general paediatrics in Manchester. Post completion of training, she undertook further subspeciality training in paediatric endocrinology and a Clinical Research Fellowship in congenital hyperinsulinism, completing a postgraduate research degree at The University of Manchester.
She was appointed as a Consultant Paediatric Endocrinologist at the Royal Manchester Children’s Hospital in 2010, and is currently the clinical lead for the Department of Paediatric Endocrinology and lead clinician for paediatric obesity, disorders of sexual differentiation and has also developed interests in metabolic bone diseases with particular focus on skeletal dysplasias.
In addition to her clinical role, she is actively involved in the training of medical students, junior medical staff and maintains a keen interest in medical research. She has previously held the post of guidelines officer for the British Society of Paediatric Endocrinology and Diabetes (BSPED), is a professor advisor for the NIHR funded obesity empowerment network (OEN) UK and have previously contributed to the development of National Institute of Health and Clinical Excellence (NICE) guidelines for obesity and quality standards.
Selected recent publications
Enhanced Islet Cell Nucleomegaly Defines Diffuse Congenital Hyperinsulinism in Infancy but Not Other Forms of the Disease.
Han B, Newbould M, Batra G, Cheesman E, Craigie RJ, Mohamed Z, Rigby L, Padidela R, Skae M, Mironov A, Starborg T, Kadler KE, Cosgrove KE, Banerjee I, Dunne MJ.
Am J Clin Pathol. 2016 Jun;145(6):757-68.
Conservatively treated Congenital Hyperinsulinism (CHI) due to K-ATP channel gene mutations: reducing severity over time.
Salomon-Estebanez M, Flanagan SE, Ellard S, Rigby L, Bowden L, Mohamed Z, Nicholson J, Skae M, Hall C, Craigie R, Padidela R, Murphy N, Randell T, Cosgrove KE, Dunne MJ, Banerjee I.
Orphanet J Rare Dis. 2016 Dec 1;11(1):163.
The neuroendocrine sequelae of paediatric craniopharyngioma: a 40-year meta-data analysis of 185 cases from three UK centres.
Tan TS, Patel L, Gopal-Kothandapani JS, Ehtisham S, Ikazoboh EC, Hayward R, Aquilina K, Skae M, Thorp N, Pizer B, Didi M, Mallucci C, Blair JC, Gaze MN, Kamaly-Asl I, Spoudeas H, Clayton PE.
Eur J Endocrinol. 2017 Mar;176(3):359-369 /EJE-16-0812. Epub 2017 Jan 10
Hormone supplementation for pubertal induction in girls.(Review)
Matthews D, Bath L, Högler W, Mason A, Smyth A, Skae M.
Arch Dis Child. 2017 Apr 26.
Vineland adaptive behavior scales to identify neurodevelopmental problems in children with Congenital Hyperinsulinism (CHI).
Salomon-Estebanez M, Mohamed Z, Michaelidou M, Collins H, Rigby L, Skae M, Padidela R, Rust S, Dunne M, Cosgrove K, Banerjee I, Nicholson J.
Orphanet J Rare Dis. 2017 May 22;12(1):96.
A heterozygous microdeletion of 20p12.2-3 encompassing PROKR2 and BMP2 in a patient with congenital hypopituitarism and growth hormone deficiency.
Parsons SJH, Wright NB, Burkitt-Wright E, Skae MS, Murray PG.
Am J Med Genet A. 2017 Aug;173(8):2261-2267
Atypical Forms of Congenital Hyperinsulinism In Infancy are Associated with Mosaic Patterns of Immature Islet Cells.
Han B, Mohamed Z, Salomon Estebanez M, Craigie RJ, Newbould M, Cheesman E, Padidela R, Skae M, Johnson M, Flanagan S, Ellard S, Cosgrove KE, Banerjee I, Dunne MJ.
J Clin Endocrinol Metab. 2017 Jun 9.