In this section
Our clinical service covers the North West of England and we run a national centre (Northern Congenital Hyperinsulinism service, NORCHI) for the rare disorder of congenital hyperinsulinism.
Our endocrine (hormone-related) research, conducted in collaboration with our main research partner The University of Manchester, focuses on growth and metabolism, bone disorders, obesity and diabetes and CHI.
Research Themes:
Growth and metabolism
- 3M syndrome and related conditions
- Pharmacogenomics of growth hormones
- Relationship between pregnancy, fetal growth and longer term growth outcomes
Bone and vitamin D disorders
- Hypophosphatasia (HPP)
- Bone architecture and muscle-bone infrastructure
- X-linked hypophosphatemic rickets
- Glucocorticoid induced osteoporosis
Obesity
Diabetes
- Type 1 and type 2 diabetes
Congenital Hyperinsulism (CHI)
- Understanding the phenotype (disease pattern) of CHI
- Improving existing medical therapies for CHI
- Understanding the pathobiology (molecular mechanism of disease) of CHI
- Identifying new targets for CHI therapy
If you are interested in finding out more about clinical research and how you can get involved, please ask a member of your medical team or visit our get involved page.