Research

As well as being busy clinically, we continue to maintain an academic profile with a significant number of publications and presentations. During 2016, 2017 and 2018 members of the department have published 29 papers in peer reviewed journals.

Please note, these are papers from members of the department but may be in conjunction with other departments within RMCH and/or other Hospitals.

  • Management strategies for idiopathic urethritis. Henderson L, Farrelly P, Dickson AP, Goyal A. J Pediatr Urol. 2016 Feb;12(1):35.e1-5.
  • Gram-negative organisms in peritoneal dialysis peritonitis: an early indication for surgery in patients with haemolytic uraemic syndrome? Harwood R, Wilkinson D, Ramkumar S, Humphrey G. Pediatr Surg Int. 2016 Mar;32(3):235-8.
  • Bridging the gap: functional healing of embryonic small intestine ex vivo. Coletta R, Roberts NA, Oltrabella F, Khalil BA, Morabito A, Woolf AS. J Tissue Eng Regen Med. 2016 Feb;10(2):178-82.
  • Non-cross-linked porcine acellular dermal matrix (Strattice Tissue Matrix) in pediatric reconstructive surgery. Begum T, Farrelly PJ, Craigie RJ. J Pediatr Surg. 2016 Mar;51(3):461-4.
  • Feeding Problems Are Persistent in Children with Severe Congenital Hyperinsulinism. Banerjee I, Forsythe L, Skae M, Avatapalle HB, Rigby L, Bowden LE, Craigie R, Padidela R, Ehtisham S, Patel L, Cosgrove KE, Dunne MJ, Clayton PE. Front Endocrinol (Lausanne). 2016 Feb 9;7:8.
  • Enhanced Islet Cell Nucleomegaly Defines Diffuse Congenital Hyperinsulinism in Infancy but Not Other Forms of the Disease. Han B, Newbould M, Batra G, Cheesman E, Craigie RJ, Mohamed Z, Rigby L, Padidela R, Skae M, Mironov A, Starborg T, Kadler KE, Cosgrove KE, Banerjee I, Dunne MJ. Am J Clin Pathol. 2016 Jun;145(6):757-68.
  • Enteric nervous system stem cells associated with thickened extrinsic fibers in short segment aganglionic Hirschsprung’s disease gut are absent in the total colonic and intestinal variants of disease. Bethell G, Wilkinson D, Fawkner-Corbett D, Mesa A, Shukla R, Edgar D, Kenny S. Journal of Pediatric Surgery. 2016.
  • Implementation of a care pathway for infantile hypertrophic pyloric stenosis reduces length of stay and increases parent satisfaction. Weatherill CV, Melling JD, Rhodes HL, Wilkinson DJ, Kenny SE. Int J Care Coordination. 2016.
  • Conservatively treated Congenital Hyperinsulinism (CHI) due to K-ATP channel gene mutations: reducing severity over time. Salomon-Estebanez M, Flanagan SE, Ellard S, Rigby L, Bowden L, Mohamed Z, Nicholson J, Skae M, Hall C, Craigie R, Padidela R, Murphy N, Randell T, Cosgrove KE, Dunne MJ, Banerjee I. Orphanet J Rare Dis. 2016 Dec 1;11(1):163.
  • Is Screening of Intestinal Foregut Anatomy in Heterotaxy Patients Really Necessary?: A Systematic Review in Search of the Evidence. Cullis PS, Siminas S, Losty PD. Ann Surg. 2016 Dec;264(6):1156-1161.
  • British Association of Paediatric Surgeons Congenital Anomalies Surveillance System Necrotising Enterocolitis Collaboration. A UK wide cohort study describing management and outcomes for infants with surgical Necrotising Enterocolitis. Allin B, Long AM, Gupta A, Knight M, Lakhoo K, (RJ Craigie, Collaborator), Sci Rep. 2017 Jan 27;7:41149.
  • Exogenous transforming growth factor-β1 enhances smooth muscle differentiation in embryonic mouse jejunal explants. Coletta R, Roberts NA, Randles MJ, Morabito A, Woolf AS. J Tissue Eng Regen Med. 2017 Jan 13.
  • Total esophagogastric dissociation: single center experience. Chhabra S, Nedea AM, Kauffman L, Morabito A. J Pediatr Surg. 2017 Feb;52(2):260-263.
  • British Association of Paediatric Surgeons Congenital Anomalies Surveillance System. Hirschsprung’s disease in the UK and Ireland: incidence and anomalies. Bradnock TJ, Knight M, Kenny S, Nair M, Walker GM (RJ Craigie, Collaborator) Arch Dis Child. 2017 Mar 9.
  • Perianal rhabdomyomatous mesenchymal hamartoma. Sampat K, Cheesman E, Siminas S. Ann R Coll Surg Engl. 2017 Jul;99(6):e193-e195.
  • Atypical Forms of Congenital Hyperinsulinism In Infancy Are Associated With Mosaic Patterns of Immature Islet Cells. Han B, Mohamed Z, Estebanez MS, Craigie RJ, Newbould M, Cheesman E, Padidela R, Skae M, Johnson M, Flanagan S, Ellard S, Cosgrove KE, Banerjee I, Dunne MJ. J Clin Endocrinol Metab. 2017 Sep 1;102(9):3261-3267
  • Transgelin-expressing myofibroblasts orchestrate ventral midline closure through TGFβ signalling. Aldeiri B, Roostalu U, Albertini A, Wong J, Morabito A, Cossu G. 2017 Sep 15;144(18):3336-3348.
  • Mortality and Morbidity in Oesophageal Atresia. Peters RT, Ragab H, Columb MO, Bruce J, MacKinnon RJ, Craigie RJ. Pediatr Surg Int. 2017 Sep;33(9):989-994.
  • Trauma Training: Mandatory “Fire Training” for General Surgeons. Smith S, Craigie R, Pollard JS, Jones DJ. RCSBull. 2017 Oct 312-315.
  • Hypospadias Surgery in England: Higher volume centres have lower complication rates.  Wilkinson DJ, Green PA, Beglinger S, Myers J, Hudson R, Edgar D, Kenny SE.  Journal of Pediatric Urology. 2017 13(5):481.
  • SERCA directs cell migration and branching across species and germ layers. Bower DV, Lansdale N, Navarro S, Truong TV, Bower DJ, Featherstone NC, Connell MG, Al Alam D, Frey MR, Trinh LA, Fernandez GE, Warburton D, Fraser SE, Bennett D, Jesudason EC. Biol Open. 2017 Oct 15;6(10):1458-1471.
  • Population-level Surgical Outcomes for Infantile Hypertrophic Pyloric Stenosis. Lansdale N, Al-Khafaji N, Greene P, Kenny S. J Pediatr Surg. 2017 May 21. pii: S0022-3468(17)30336-6.
  • Active observation versus interval appendicectomy after successful non-operative treatment of an appendix mass in children (CHINA study): an open-label, randomised controlled trial. Hall, NJ, Eaton, S, Stanton, MP, Pierro, A, Burge, DM, and on behalf of the CHINA study collaborators and the Paediatric Surgery Trainees Research Network.. Lancet Gastroenterol Hepatol. 2017; (published online Feb 6.) (N Lansdale collaborator).
  • Early population-based outcomes of infants born with congenital diaphragmatic hernia. Long AM, Bunch KJ, Knight M, Kurinczuk JJ, Losty PD; BAPS-CASS. Arch Dis Child Fetal Neonatal Ed. 2018 Nov;103(6):F517-F522. (D Wilkinson & R Craigie collaborators).
  • Controversies in the management of ovarian tumours in prepubertal children – A BAPS and UK CCLG surgeons cancer group national survey. Braungart S, Craigie RJ, Losty PD. J Pediatr Surg. 2018 Nov;53(11):2231-2234.
  • Trisomy 18: palliative surgical intervention. Spierson H, Masood Y, Craigie RJ, Edi-Osagie N. Arch Dis Child. 2018 Oct;103(10):1001.
  • Manchester Arena Bombing: lessons learnt from a mass casualty incident. Craigie RJ, Farrelly PJ, Santos R, Smith SR, Pollard JS, Jones DJ. J R Army Med Corps. 2018 Apr 6. Pii:jramc-2018-000930. [Epub ahead of print].
  • Clinical Diversity in focal congenital hyperinsulinism in infancy correlates with histiological heterogeneity of islet cell lesions. Craigie RJ, Salomon-Estebanez M, Yau D, Han B, Mal W, Newbold M, Cheesman E, Bitetti S, Mohammed Z, Sajjan R, Padidela R, Skae M, Flanagan S, Ellard S, Cosgrove KE, Banerjee I, Dunne MJ. Front Endocrinol (Lausanne). 2018 Oct 17;9:619.
  • Transanastomotic tubes reduce the cost of nutritional support in neonates with congenital duodenal obstruction. Harwood R, Horwood F, Tafilaj V, Craigie RJ. Pediatr Surg Int. 2018 Nov 11 [Epub ahead of print].
  • Prospective evaluation of a clinical response directed pathway for complicated appendicitis. Lansdale N, Fryer S, Stockdale M, Bancroft J, Orr J, Corbett H, Kenny S. J Pediatr Surg. 2019 Feb;54(2):272-275One-year outcomes for congenital diaphragmatic hernia. Lansdale N, Wilkinson D. BJS Open. 2019 May 9;3(3):415-416.
  • One-year outcomes of infants born with congenital diaphragmatic hernia: a national population cohort study. Long AM, Bunch KJ, Knight M2, Kurinczuk JJ, Losty PD; BAPS-CASS. (D. Wilkinson and R Craigie collaborators) Arch Dis Child Fetal Neonatal Ed. 2019 Jun 1. pii: fetalneonatal-2018-316396.Paediatric.
  • Horner’s syndrome: is investigation for underlying malignancy always required? Arch Dis Child. 2019 Oct;104(10)984-987. Braungart S, Craigie RJ, Farrelly P, Losty PD.
  • Outcome and prognostic factors in paediatric malignant peripheral nerve sheath tumors: An analysis of the European Pediatric Soft Tissue Sarcoma Group (EpSSG) NRSTS-2005 prospective study. van Noesel M, Orbach D, Brennan B, Kelsey A, Zanetti I, de Salvo GL, Gaze MN, Craigie RJ, McHugh K, Francotte N, Collini P, Bisogno G, Casanova M, Ferrari A. Pediatr Blood Cancer. 2019;Oct 66(10):e27833.
  •  Ovarian tumors in children: how common are lesion recurrence and metachronous disease? A UK CCLG Surgeons Cancer Group nationwide study. Braungart S, CCLG Surgeons Collaborators, Craigie RJ, Farrelly P, Losty PD. J Pediatr Surg. 2019 Nov 26. pii: S0022-3468(19)30794-8. [Epub ahead of print].
  • Transanastomotic tubes reduce the cost of nutritional support in neonates with congenital duodenal obstruction. Harwood R, Horwood F, Tafilaj V, Craigie RJ.. Pediatr Surg Int. 2019 Apr;35(4):457-461.
  • Congenital duodenal obstruction in the UK: a population-based study. Arch Dis Child Fetal Neonatal Ed. 2019 Jun 22. pii: fetalneonatal-2019-317085. Bethell GS, Long AM, Knight M, Hall NJ; BAPS-CASS. (R Craigie collaborator).
  • Variations in the Detection of Anorectal Anomalies at Birth among European Cities. Aldeiri B, Davidson JR, Eaton S, Coletta R, Cardoso Almeida A, Long AM, Knight M, Cross KM, Chouikh T, Iacobelli BD, Sarnacki S, Bagolan P, Cretolle C, Siminas S, Curry JI, Morabito A, De Coppi P. Eur J Pediatr Surg. 2019 Apr 30.
  • Intrathoracic renal ectopia with congenital diaphragmatic hernia. Peterson JLH, Riggs H, Nedungadi S, Lansdale N, Kamupira S. Arch Dis Child Fetal Neonatal Ed. 2019 May;104(3):F320.
  • Central venous catheter-associated thrombosis in children with congenital hyperinsulinism. Yau D, Salomon-Estebanez M, Chinoy A, Grainger J, Craigie RJ, Padidela R, Skae M, Dunne MJ, Murray PG, Banerjee I. Endocrinol Diabetes Metab Case Rep. 2019 Jul 9;2019(1).
  • Operative management of pediatric ovarian tumors –  the challenge of fertility-preservation. Results from the UK CCLG Surgeons Cancer Group Nationwide Study. Braungart S, Craigie RJ, Farrelly P, Losty PD. J Pediatr Surg. 2020. Accepted for publication.
  • Khandwalla Z, Tanney K, Gasiorowski E, Lansdale N, Wilkinson D. Communicating bronchopulmonary foregut malformation 1a: imaging and approach. Arch Dis Child Fetal Neonatal Ed. 2020 Jul;105(4):444.  doi: 10.1136/archdischild-2019-318681. Epub 2020 Mar 27.
  • Ducey, J., Wilkinson, D.J., Peters, R.T, Craigie RJ, Farrelly PJ, Lansdale N. Laparoscopic cholecystectomy by paediatric surgeons: can established standards of care be delivered?. J Ped Endosc Surg 2, 117–121 (2020). https://doi.org/10.1007/s42804-020-00063-9
  • Sharif B, Wilkinson D, Zaparackaite I, Lansdale N. Superior vena cava injury during central venous catheter insertion in a young child: recognition and minimally invasive management BMJ Case Reports CP 2020;13:e236694.

Book Chapters & Other Publications

  • Anders NRK, Bowes LJ and Craigie RJ. 2016. Principles of paediatric surgical care. In: Oxford Textbook of Fundamentals of Surgery. Oxford University Press pp. 725-734
  • Morecroft JA and Craigie RJ. 2016. Common paediatric surgery conditions. In: Oxford Textbook of Fundamentals of Surgery. Oxford University Press pp. 741-746
  • Lansdale N, Orr J. Patient information sheet: ‘Surgery for the impalpable testicle.’ International publication by EIDO Healthcare Ltd. 2017.