Allergies
An allergy is an undesirable potentially severe or even life-threatening reaction to a substance that normally is harmless (and which has no effect in non-allergic individuals). Such substances are called allergens. Some of the most common allergens include:
- Aeroallergens: grass, tree and weed pollen, house dust mites, furry animals, moulds
- Foods: common examples are peanut and tree nuts, shellfish, fruits, eggs and dairy
- Medications: antibiotics (e.g. penicillin), NSAIDs (e.g. aspirin, ibuprofen), general anaesthetics, etc.
What does the Allergy Centre offer?
We provide a service for the diagnosis of the full spectrum of allergic conditions, offering a unified approach to their management. This means we assess and manage all allergic problems patients may have and formulate a management plan that addresses these and takes into account their other medical conditions, with the aim to improve their health and quality of life.
We perform diagnostic skin tests, laboratory tests (blood) and challenge tests to foods, drugs, bee/wasp venoms, latex; in some patients, we offer desensitisation (or allergen immunotherapy) for bee and wasp venom allergy, inhalant allergy (or rhinoconjunctivitis) for allergens such as pollen, mites, or cats, and desensitisation to drugs such as aspirin. We also perform diagnostic food and drug challenges where appropriate.
Correct diagnosis of an allergy means we can help you take the right steps to properly manage your condition.
We accept referrals for adults and children with the following conditions:
- allergic rhinoconjunctivitis, such as pollen allergy (hay fever), allergy to animals, allergy to house dust mites
- food allergy (we do not routinely investigate food intolerances)
- anaphylaxis
- insect venom allergy (bee and wasp)
- drug allergy /hypersensitivity, including perioperative anaphylaxis
- vaccine allergy
- urticaria and angioedema
- asthma
- latex allergy
- eczema
- mastocytosis and related disorders
When and where are the clinics held?
All the clinics are held at the Allergy Centre (F10), Wythenshawe Hospital, Manchester University NHS Foundation Trust. Patients are initially seen in the General Allergy Clinic and referred to other specialist clinics if and when appropriate.
General Allergy Clinic
Held most days of the week and run by doctors specialised in allergy or with an interest in allergy (Dr Susana Marinho, Dr Marina Tsoumani, , Dr Iason Thomas, Dr Samia Azmi, Dr Ching Ching Yung, Professor Angela Simpson) and specialist allergy nurses (Ms Jenny Addison, Ms Caisha Johnson, Ms Hollie Weller, Ms Sosamma John).
Allergy and Asthma clinic
Run by Professors Angela Simpson, Ashley Woodcock and Hannah Durrington. Adults discharged following admission with acute asthma are routinely reviewed in the clinic, where they undergo lung function testing, allergy testing and education. Close links exist with the severe asthma service via a monthly MDT.
Joint Paediatric Allergy Clinic
Held every 4th Monday afternoon of the month with Dr Naveen Rao (Consultant Paediatrician) and Dr Susana Marinho (Consultant Allergist).
Dr Naveen Rao runs weekly paediatric allergy clinics. This clinic is ideal for infants and children with food allergies.
Nut Allergy Clinic
Held once per month and run by Dr Marina Tsoumani; this is a dedicated clinic for individuals with peanut and tree nut allergies.
Severe Urticaria Service
Held weekly and run by Dr Susana Marinho, Dr Marina Tsoumani, Dr Iason Thomas, Dr Samia Azmi and Dr Ching Ching Yung for assessment and treatment of patients with severe chronic urticaria and angioedema. Treatment with omalizumab is also provided to eligible patients.
Allergen Immunotherapy Service
Patients are given allergen immunotherapy (desensitisation) to allergens such as bee/wasp venom, tree, grass or weed pollens, dust mites, cat, dog, horse, etc.
Drug Allergy Investigation Service
Patients are investigated and skin tested to drugs or bee/wasp venoms. Investigation of perioperative anaphylaxis is offered within this service. Held on most afternoons of the week (Dr S Marinho, Dr M Tsoumani, Dr Iason Thomas, Dr Samia Azmi and Dr Ching Ching Yung).
Day Cases – Challenges
Provocation challenges with foods or drugs are carried out to investigate allergies and/or find suitable alternatives. Desensitisation to drugs is also carried out. Held daily and run by Dr Susana Marinho, Dr Marina Tsoumani, Dr Iason Thomas, Dr Samia Azmi and Dr Ching Ching Yung.
Future service development
The Allergy Centre is actively engaged in service development and national discussions relating to emerging treatments for food allergy, including desensitisation approaches.
At present, food desensitisation is not routinely available within our service. Any future service development will be subject to national guidance, commissioning decisions, regulatory approvals, and appropriate governance processes.
Patients will continue to receive evidence-based assessment, diagnosis, education, and avoidance advice in line with current UK guidance.
Perioperative Anaphylaxis Service
We investigate cases of suspected perioperative anaphylaxis with blood and skin tests, as well as drug challenges wherever appropriate. We run a regular perioperative anaphylaxis MDT with Dr Andrew Parkes (Consultant Anaesthetist) to discuss all cases, agree on diagnoses and culprits and formulate a detailed plan including drugs/substances to avoid and suggested drugs for future procedures.
Dietetic Service
Held once per week and run by a dietitian with a special interest in allergy, Ms Lydia Hudson. This service provides advice to patients with food allergies. This service provides patients with better understanding of their food allergies, a detailed plan for food avoidance diets (with useful hints and tips on how to manage this) and suitable alternative options for maintaining a nutritionally balanced diet despite food exclusions.
Psychology Service
Held twice per week and run by a Clinical Psychologist with a special interest in allergy, Dr Azza Aglan. Living with allergies can be a very distressing experience and can significantly impact on patients’ quality of life. Because allergies are often complex problems, which can affect people in many different ways, a thorough assessment is very important to support them to identify ways of coping to manage their life living with allergies.
This service provides psychological support and advice to patients suffering with allergies; the aim of any psychological intervention is not to treat the allergy symptoms themselves but to help patients explore and discover what things in life are important and meaningful to them and what factors past and present are standing in the way of them being able to achieve their goals. Learning new ways of coping will help them to gradually regain control of their life despite the impact of allergy.
This service makes an invaluable contribution to the holistic approach to patients that the Allergy Centre is strives to offer.
Greater Manchester Rapid Access Anaphylaxis Clinic
We also run the Greater Manchester Rapid Access Anaphylaxis Clinic. Patients presenting, a potentially life-threatening severe allergic reaction, need appropriate post-anaphylaxis care (in accordance with guidance from NICE – the National Institute for Health and Care Excellence).
This clinic is for patients presenting to Emergency Departments of other Greater Manchester hospitals with suspected anaphylaxis only, an appointment within seven days of referral for post-anaphylaxis care. We provide this in collaboration with the Immunology and Allergy service at Manchester Royal Infirmary, Manchester University NHS Foundation Trust.
What should you expect from the GMRAAC appointment?
- A focussed assessment of what happened during the recent reaction
- A review of the documentation from the recent reaction
- An additional blood sample may be required – but this will not be for an allergy test
- Advice on how to manage any future allergy including what to do, when to call for help and how to use anti-allergy medications
- Discussion and advice on avoidance, if a clear trigger is identified
- To plan allergy investigations, if required (allergy investigations cannot be carried out this close to a reaction and are usually carried out no sooner than 4 to 6 weeks after)
What not to expect from the GMRAAC appointment
- Allergy tests will not be carried out at this initial assessment as they are not reliable this close to an allergic reaction
- An extensive review of all possible or past allergies or any other unrelated health problems
Referral from Emergency Departments to GMRAAC
Service facilities and accommodation
The Allergy Centre is a dedicated, purpose-designed clinical facility within Wythenshawe Hospital.
The Centre comprises six consulting rooms, a treatment and lung function room, two clinical suites for day cases, a preparation room, a patient waiting area, and dedicated office space for clinical and administrative staff, with a staff rest area to support day-to-day service delivery. The preparation room is used to support drug and venom skin testing, supervised food and drug challenges, drug desensitisation and allergen immunotherapy. It is equipped with refrigeration and freezer storage for relevant medicines, including allergen immunotherapy and biologic therapies, and for preparation and storage of food items required for supervised food challenges, including threshold and blinded challenges where appropriate. Drug and food handling is undertaken in accordance with Trust infection control, medicines management and food hygiene and policies and procedures.
The Centre provides integrated access to consultation rooms, treatment and procedure areas, phlebotomy, and facilities for diagnostic testing, including spirometry, peak expiratory flow measurement, fractional exhaled nitric oxide (FeNO), and assessment of inducible urticaria.
Day-case facilities are available for supervised drug and food challenges, drug desensitisation, allergen immunotherapy administration, and investigation of complex allergic reactions, including perioperative anaphylaxis.
The Allergy Centre is supported by Trust-wide emergency, critical care, and diagnostic services, ensuring safe delivery of specialist allergy care.
Accessibility
The Allergy Centre is fully accessible, and detailed, up-to-date accessibility information (including access routes, parking, entrances, lifts, and facilities) is available via the Accessable website.
Education and Training
The Allergy Centre plays a significant role in allergy education and training across undergraduate, postgraduate, and specialty levels, contributing locally, regionally, and nationally.
The service is a recognised training site for Allergy and Clinical Immunology specialty training, supporting two Allergy (ACI) specialty trainee posts, and contributes to national training activity, including BSACI national training days for allergy trainees.
In addition, the Allergy Centre delivers structured allergy teaching for trainees in Respiratory Medicine, ENT, Acute and Internal Medicine, as well as Internal Medicine Trainees (IMTs) and Emergency Department doctors, with a particular focus on anaphylaxis recognition and integrated care pathways.
Regular teaching is also provided for Foundation Year doctors, GPs, and medical students, including student-selected components and allergy-focused educational programmes.
The service contributes to specialist education for Clinical Immunology STP trainees and MSc programmes in Allergy and Immunology, including teaching roles linked to the University of Manchester and Imperial College London.
Research
The Allergy Centre is actively involved in clinical and translational research in allergy and immunology. Consultants within the service contribute to research studies as principal investigators and co-investigators, and the service supports participation in ethically approved research studies in accordance with Trust research governance processes.
Current and recent research activity includes studies in chronic urticaria, food allergy, drug allergy, anaphylaxis, and allergic respiratory disease, as well as evaluation of emerging therapies, including biologic and novel treatment approaches, where appropriate. The service also participates in large national audit- and research-linked programmes, including NAP6 (the Sixth National Audit Project of the Royal College of Anaesthetists, focusing on perioperative anaphylaxis) and PAFA (Patterns of Adult Food Allergy), an FSA-funded national research study. We are a centre for GIANTLEAPS, a Horizon Europe grant investigating adverse reactions to alternate proteins.
The Allergy Centre has strong academic links with the University of Manchester, supporting research activity, postgraduate education, and trainee involvement in research and quality improvement projects. Educational activity is supported by regular feedback, which consistently highlights high levels of engagement, clarity, and relevance to clinical practice.
You can learn about our leading research work, how this benefits patients, and how you can get involved, by visiting our clinical research facility pages.
Referral Information
For patients
If you are worried about an allergy, ask your GP to refer you to the Allergy Centre.
For GPs and Specialists
Please see the management and referral pathways for common conditions below if you are considering a referral to our service.
Referrals from Primary Care
Referrals from Primary Care must be sent through the NHS e-Referral System.
Specialist referrals
can be sent via post –
Allergy Centre, Wythenshawe Hospital (F10)
Wythenshawe Hospital
Southmoor Rd
M23 9LT
or email –
Referral pathways and guidance
Referral from Emergency Departments to GMRAAC
Contact Us
Tel: 0161 291 4055
Fax: 0161 291 4057
Email: mft.AllergyCentre@nhs.net
AllergyCentre@mft.nhs.uk (for internal referrals only)
Address:
Allergy Centre, Wythenshawe Hospital (F10)
Wythenshawe Hospital
Southmoor Rd
M23 9LT
Location:
The Allergy Centre is located in F10 within the main hospital site at Wythenshawe Hospital.
Please allow at least 15-20 minutes from parking/entrance to reach the Allergy Centre.
Car parking at Wythenshawe Hospital is extremely limited for patients, visitors, and staff. In line with local green transport initiatives, visitors are strongly encouraged to consider alternative means of travel or to use off-site public parking. A public car park is available on Floats Road (Floats Rd Public Car Park, M23 9NJ), located adjacent to the hospital.
Allergy Centre Team
Consultants
| Dr Susana Marinho | Consultant Allergist & Clinical Lead of the Allergy Centre |
| Dr Marina Tsoumani | Consultant Allergist |
| Dr Iason Thomas | Consultant Allergist |
| Dr Samia Azmi | Consultant Allergist |
| Dr Ching Ching Yung | Consultant Allergist |
| Professor Angela Simpson | Professor of Respiratory Medicine |
| Professor Ashley Woodcock | Professor of Respiratory Medicine |
| Professor Hannah Durrington | Professor of Respiratory Medicine |
Resident Doctors – Specialty Trainees in Allergy and Clinical Immunology
| Dr Harriet Roberts | Allergy & Clinical Immunology Specialty Trainee |
| Dr Sook Yin Loh | Allergy & Clinical Immunology Specialty Trainee |
Nurses
| Ms Jenny Addison | Allergy Nurse Specialist |
| Ms Hollie Weller | Allergy Nurse Specialist |
| Ms Caisha Johnson | Allergy Nurse Specialist |
| Ms Sosamma John | Allergy Nurse Specialist |
| Ms Tessy Kunnassery | Staff Nurse |
| Ms Katie Shuttleworth | Staff Nurse |
| Ms Olivia Chen-Bacchus | Staff Nurse |
| Ms Jisha Lukose | Staff Nurse |
| Vacant | Staff Nurse |
Allied Health Professionals
| Ms Claire Wright | Allergy Dietitian |
| Ms Lydia Hudson | Allergy Dietitian |
| Dr Azza Aglan | Principal Clinical Psychologist – Allergy |
Health Care Assistants
| Ms Mariola Zmudzka | HCW |
| Ms Shanna Bingham | HCW |
| Ms Sidra Nazir | HCW |
Administrative Staff
| Ms Christine Reilly | Allergy Office Manager |
| Ms Christine Gillett | Allergy Secretary |
| Ms Alison Jenkinson | Allergy Secretary |
| Mr Clive Stevens | Allergy Secretary |
| Ms Joanna Bagnall | Allergy Bookings & Waiting List Clerk |
| Mr David Coppel | Allergy concierge/caretaker |
Consultants
- Dr Samia Azmi - Consultant Allergist
- Professor Hannah Durrington - Professor of Respiratory Medicine
- Dr Susana Marinho - Consultant Allergist and Clinical Lead of the Allergy Centre
- Professor Angela Simpson - Professor of Respiratory Medicine
- Dr Iason Thomas - Consultant Allergist
- Dr Marina Tsoumani - Consultant Allergist
- Professor Ashley Woodcock - Professor of Respiratory Medicine
- Dr Ching Ching Yung - Consultant Allergist