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This section details information for the requesting of investigations, specimen requirements and communication of results for the department of Paediatric Histopathology. Paediatric Histopathology is situated on the 4th floor of the Royal Manchester Children’s Hospital.

Our department deals with approximately 5,000 surgical cases and around 400 autopsies annually. Our department comprises approximately over 27 medical, scientific and ancillary staff. We have IBMS training status and support local universities in the training of Biomedical Science students.

We are committed to providing a high quality and timely regional histopathology service and contribute to the HM Coroner’s service.

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Services offered

The laboratory offers a full range of histopathology techniques for children. These include:

  • Routine diagnostic histopathology: Renal biopsies (native and transplant), Gastrointestinal biopsies and resections, skin biopsies and excisions, Bone Marrow trephines, Placentas.
  • Tumour biopsies and resections
  • Rapid frozen section service for rectal suction biopsies in cases of suspected Hirschsprung’s disease
  • Intraoperative diagnosis for a range of clinical scenarios: Hirschsprung’s disease and Congenital hyperinsulism
  • Enzyme histochemistry, including muscle histochemistry on both Paediatric and Adult patients
  • Immunohistochemistry
  • Fluorescent In Situ Hybridisation (FISH) for soft tissue tumours and neuroblastomas (turnaround time of 3-4 days)
  • Immunofluorescence for Renal Biopsies
  • Immunofluorescence for Skin Biopsies
  • Electron microscopy via the electron microscopy suite in Clinical Sciences Building
  • Molecular diagnostics (turnaround time 3-7 days) via Genetics 6th floor St Mary’s
  • Non-gynae cytology – we perform a limited range of tests: to detect the presence of malignant cells, eosinophils, lipid or haemosiderin laden macrophages within fluid samples from paediatric patients. Please note we do not perform cell counts.
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Opening hours

The laboratory is open between 08:30 and 17:30 Monday to Friday excluding Bank Holidays.

There is no regular on-call service for histopathology laboratory staff, though we do try to accommodate requests for out of hours urgent work wherever possible.

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Location

The department is located on levels 3, 4 and 5. The Consultants, main laboratory and secretarial office are situated on the 4th floor of Royal Manchester Children’s Hospital, lift core 7, next to pharmacy.

The Giving for Living laboratory is situated above on the 5th Floor

The Paediatric Mortuary is on the 3rd floor Royal Manchester Children’s Hospital, lift core 8.  Please see the separate User Guide.

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Contact information

Address

Diagnostic Paediatric Histopathology Service
4th Floor
Royal Manchester Children’s Hospital
Oxford Road
Manchester M13 9WL

0161 701 2240

Histology Reports

Email: paed.hist@mft.nhs.uk

NHS mail: mft.rmch.paedhist@nhs.uk

Histology reports can be accessed on HIVE. Queries should be directed to the departmental e-mail account paed.hist@mft.nhs.uk.

Laboratory Enquiries

All enquiries regarding frozen sections, specimen requesting, labelling, transport and requirements should be directed to the main histology laboratory.

Telephone – 0161 701 2240

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(Last reviewed August 2024)